There could be another explanation than just hormones behind this trend, according to a scientist at Johns Hopkins Bloomberg School of Public Health Sabra Klein.
To test whether female hormones prove effective as a treatment, doctors in California and New York are treating COVID-19 patients with female hormones: progesterone in Los Angeles and estrogen on Long Island. An attempt to find another possible treatment for COVID-19 through hormones is underway. The Long Island estrogen study at Stony Brook University will have 110 emergency room patients (with both men and women having COVID-19 symptoms), but do not require ventilators. The Los Angeles Cedars-Sinai progesterone study has 40 men already admitted to the hospital for COVID-19, mentioned the New York Times.
As pulmonologist and physician at Cedars-Sinai hospital Dr Sara Ghandehari told the New York Times, “There’s a striking difference between the number of men and women in the intensive care unit, and men are clearly doing worse.” Men make up about 75% of Cedars-Sinai patients in intensive care and on ventilators due to COVID-19.
It is noteworthy that both hormones - Estrogen and progesterone - improve the immune system. These could also help researchers and doctors understand why the impact of COVID-19 is gender sensitive.